"Construction and characterization of C-activator. (A) Levels of mRNAs encoding growth factor HGF, EGF, IGF-1 and HSS were quantified using RT-qPCR ( n = 3; mean ± SD). (B) Levels of mRNAs encoding repair factor IL-4, IL-13, TGF-β and VEGF were quantified using RT-qPCR ( n = 3; mean ± SD). (C) Schematic diagram of the cocktail activator to realize hepatocyte rescue and inflammation modulation by DMI-loaded liposomes modified with DG. (D) Particle size distribution and TEM image of C-activator. Scar bar is 200 nm. (E-F) Mean fluorescence intensity and flow cytometry graphs of cellular uptake of RhB-Lip (32 µg/ml) by <t>LO2</t> cells after incubation for 1, 2, 4, 6, 8 and 10 h ( n = 3; mean ± SD). * P < 0.05, ** P <0.01, *** P < 0.001, **** P < 0.0001 compared with APAP group by one-way ANOVA test or two-way ANOVA test. "